Benzodiazepines can be very effective for anxiety disorders, panic disorder, insomnia, alcohol use disorder, and seizures, however, they also come with many side effects, especially in those with chronic liver disease or alcohol abuse disorder. Benzodiazepines like Xanax and Valium have a high-risk potential for drug abuse and dependence. Long-term benzo abuse can lead to higher liver enzyme levels, hepatic injury, and liver damage.